Lupus eritematoso sistemico pediatrico sciencedirect. Protocolo clinico e diretrizes terapeuticas lupus eritematoso. Abstract systemic lupus erythematosus sle is an autoimmune disease that is more severe in pediatric population than in adults. Lupus eritematoso sistemico julia garciaconsuegra molina 9 manifestaciones clinicas sindrome constitucional. Sus manifestaciones varian desde afecciones leves a graves o fatales. Es lupus eritematoso sistemico les es una enfermedad, potencialmente fatal y facilmente confundible con muchas otras condiciones. O lupus eritematoso sistemico pode apresentar inumeras lesoes cutaneas. Bullous systemic lupus erythematosus bsle is a rare manifestation of. Ocurre en todas las razas, con cierto predominio en mujeres 2. Articulo original complicaciones en pacientes con lupus. Systemic lupus erythematosus sle is an autoimmune disease in which organs, tissues and cells are damaged by immune complexes. Es mas comun en mujeres y su prevalencia varia entre 40 a 200 casos100.
Ultraviolet radiation is the environmental factor most linked to lupus, and causes exacerbation in 70% of patients to increase apoptosis of keratinocytes and other cells or by altering the dna and intracellular proteins so they become antigenic. Abstract pediatric systemic lupus psle is a chronic multisystemic autoinmune disease with complex clinical manifestations and special issues, which need to be considered when dealing with sle in children. Systemic lupus erythematosus sle is an autoimmune disease of unknown origin that causes outbreaks epi sodes alternating with periods of remission. Las lesiones inespecificas fotosensibilidad, aftas orales, nodulos subcutaneos, alopecia son. A doenca pode ser diagnosticada em qualquer idade, mesmo em lactentes.